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can someone explain D-bol...?

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giantkilr

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can someone explain D-bol...?

Post by giantkilr on Wed Apr 05, 2017 1:30 pm

hey,
i know that d-bol is used for bulking, which is what i am going to use it for...but what does it do exactly...& what is the best way to use it...?
thanks. Question


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pincrusher

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Re: can someone explain D-bol...?

Post by pincrusher on Wed Apr 05, 2017 2:04 pm

here is some info for ya:

Dianabol



Pharmaceutical Name: Methandrostenolone / methandienone
Chemical structure: 17 beta-hydroxy-17alpha-methyl-1,4-androstadien-3-one
Effective dose: 15-50 mg / day orally or 50-150 mg / week by injection
Average Street-price: $0.35 - 1.00 per 5 mg tab
Available Doses: 1,2, 5 and 10 mg tabs or 25 mg/ml in 50 ml vials



Characteristics:

Dianabol was originally developed by John Ziegler and released by Ciba in 1956. It has had a long stint of popularity since then, especially in the US. Until the late 70's methandrostenolone was all the rave. Perhaps the most popular steroid ever. Known users include every Mr.Olympia from Scott to Zane. Of course the doses used have severely increased since then. Its popularity was also the cause of its demise. Almost a decade ago now the original D-bol was discontinued when the FDA drew the conclusion that its therapeutic uses were minimal compared to the amount of bodybuilders who were using it. But methandrostenolone has never been out of circulation really. Especially the Russians appeared quite fond of it and Russian D-bol is one of the best and most marketed forms of the substance methandrostenolone today.

Methandrostenolone is without a doubt one of the best, if not the best product for people who compete in non-aerobic oriented sports. It promotes drastic protein synthesis, enhances glycogenolysis (repletion of glycogen after exercise) and stimulates strength in a very direct and fast-acting way. It may be less useful to those competing in aerobic events as it also diminishes cell respiration1. But methandrostenolone manifests itself in a distinct manner : rapid and fast-acting build-up of strength and mass is noticed. That's why its often used at the beginning of cycle consisting of mostly injectables like long-acting testosterone esters and nandrolone. Since the effects of such drugs don't fully come out for the first 10-15 days, methandrostenolone is dosed in to provide immediate and visible results. It has a rather weak androgenic component and an obviously quite strong and visible anabolic component. Its effects are largely non-AR mediated, which is documented by its rather low influence on the natural endocrine system2 and the fact that it decreases rather than increases red blood cell content in the blood. Which means that one worry users of Dianabol, especially short term, needn't fear is the dramatic shutdown of natural testosterone production as is often the case with very androgenic compounds. Of course this effect is dose-dependent. It still has a mild androgenic component, meaning in high doses (30+ mg daily) androgen-mediated side-effects can be noted (acne, male pattern hair loss).

Because of its fast effects, immense popularity and the increasing "more-is-better" sentiment among bodybuilders, increasingly high doses are indeed being used and recommended. One has to wonder about the logic of such recommendations however, since high dose urine-analysis showed portions of unmetabolized compounds were being excreted3. In simpler terms that means that with higher doses, higher amounts of unchanged methandrostenolone were being excreted in the urine. This would indicate that the current stance needs to be reviewed and that smaller doses, taken multiple times per day would deliver better results and maximal use of the steroid. Dianabol simply is highly effective in low doses(25-40 mg ed). Som say Anadrol, a comparable steroid to methandrostenolone, is better, but its taken in doses of 50-150 mg. If one was to take methandrostenolone in those doses better gains could be expected. Methandrostenolone is also a lot safer in as opposed to the highly toxic and progestagenic anadrol. If one takes into account that the half-life of methandrostenolone in the body is only 3-6 hours, this theory makes even more sense. So taking your daily dose spread over 3 or 4 doses may elicit a better effect than only 1 or 2 doses. Methandrostenolone is quite effective in these lower doses by the way. Milligram for Milligram its more powerful than a testosterone ester, generally considered the best mass-builder.

A few notes there need to be made however. Not everyone should try and spread their doses out over multiple servings. First of all there is a slightly lower efficacy to take into account here as well due to two characteristics. The first being that you feed the total amount to the liver in smaller portions, yet the liver still manages to metabolize the same amount. Percentage wise that means less methandienone would make it through totally. The second would be that the peak levels aren't quite as high since no large doses are taken all at once. These two facts make it hard to recommend that just anyone take multiple doses. People who take moderate to low doses of ONLY methandrostenolone should probably opt for a single morning dose. This delivers a higher peak level and more survival of your only steroid. It also, due to the short half-life, makes the drug clear the body before the body produces its largest dose of natural testosterone, the early hours of sleep. Combined with the already mild effect at the AR, you could keep a good amount of your gains when using clomid or Nolvadex post-cycle. For those using it in conjunction with other, mostly injectable steroids, two doses seems to be the better choice, if you are taking in excess of 40 mg a day perhaps even three doses.

This is usually the case for fast-acting substances, they have short half-lives. Which brings us to the point of prolonged use. The general concensus is that methandrostenolone should never be used more than 6 weeks on end due its strong hepatoxic effects. Being largely an oral compound, its also 17-alpha-alkylated to help it survive the liver upon first pass. Liver values are elevated over a short period of time4, making long-term use a very dangerous affair. Liver values should return to normal quite fast after discontinuation however since the effects are so short-lived. Other risks associated with the use of methandrostenolone include the apparition of estrogenic side-effects because it interacts rather well with the aromatase enzyme on account of its methylated properties. It is therefore best used in conjunction with an anti-estrogen. Gynocomastia, high blood pressure, salt and water retention and mild cases of acne are therefore not uncommon.

Its methylated properties (17-methyl group) does have several positive characteristics of course. Why else would they add this group? The main purpose of course it to make sure less of the methandrostenolone is affected by hepatic breakdown when taken orally. But apparently it also decreases the affinity of the drug to SHBG (sex-hormone binding globulin), a sex steroid binding protein that takes up as much as 98% of testosterone. Testosterone that can't be used to build muscle. Since methandrostenolone does not bind to this protein easily, its quite an active substance, no doubt accounting for its fast and immediately visible action. Dianabol also does not affect cholesterol levels to a high degree in moderate doses5, and it seems to help an athlete stock up on potassium6. This is particularly beneficial taking into account the amount of sodium its estrogenic effects store as well.

We hinted at the short time of activity methandrostenolone possesses. This means that despite its immediate, fast and explosive gains in both strength and mass, they are quite hard to maintain. Often the bulk of mass is lost shortly after discontinuation, making it most unsuitable for those looking to gain and keep quality muscle. An injectable may suppress some of these obviously flawed characteristics, but the 5 mg tabs remain the trend. With its high capacity to survive breakdown in the liver this understandably. Orally its perhaps the most powerful, although in the strength of effects it still can't hold a candle to androl. But its cheaper and safer than the aforementioned of course.

In light of the evidence presented, we conclude that the best use for methandrostenolone is short-term, for 5-6 weeks, at the beginning of a longer bulking stack (10+ weeks), preferably injectable, to kickstart gains and strength. Its effects are largely non-AR mediated and it aromatizes quite well, which leaves it with limited stacking partners, The best candidates are of course nandrolone and testosterone. It should be taken in doses no higher than 50 mg (20-40 mg being the norm) ,spread over multiple doses for maximum effects in stacks and a single morning dose when taken by itself. D-bol remains a favorite today however, that's a fact that cannot be argued.

Stacking and Use:

I needn't really expand too much, since most of the conclusion were drawn in that last paragraph. Dianabol is a methylated compound with a certain toxicity, so in the interest of safety you wouldn't use it longer than 6 weeks on end, 8 weeks at the absolute maximum and only under supervision of a medical professional who can monitor your liver values. Because it heavily aromatizes its not particularly useful during cutting and with 6-8 weeks of use maximum, that leaves but two options. Either stacking it with another, injectable, compound that can be used for longer terms (beginning of stack when other compound is least active) or you would do multiple short cycles. In that case one would take off at least as long as he was on during a cycle, preferably longer. Like 6 weeks on, followed by 6-10 weeks off. These multiple cycles were all the fashion among pro bodybuilders in the 70's with very decent results.

When stacking with a longer-acting product, such as testosterone enanthate or cypionate, Deca or Equipoise, the best use is early on in the stack. Dianabol is a very fast-acting steroid and most injectables don't start showing their real value for 2-3 weeks. That makes it particularly useful to kick off a cycle with.



The pink ones are Anabol (Dianabol) and the yellow ones are Stanabol (Winstrol). These are very popular right now. They are 5 mg tabs and they sell for less than 30 cents a tab.
It's most readily stacked with Deca-Durabolin or Primobolan, perhaps even Equipoise. Usually an injection of 200-400 mg/week combined with 30-40 mg of Dianabol everyday. In some cases testosterone was used in conjunction with anyone of these stacks. For short term use oral Primobolan made a good match, and in lesser ways an oral Winstrol. Both provide a mild, lean foundation for the Dianabol and both are also 17-alpha alkylated, warranting short-term use. Since Dianabol has little Androgen receptor activity, it functions particularly synergistic with compounds that have a strong Androgen receptor activity as is the case for all the aforementioned.

Along the lines of secondary products an anti-aromatase like Cytadren or Arimidex may be useful. When stacked with Deca, the choice for a receptor antagonist like Clomid or Nolvadex is perhaps a wiser choice. Perhaps even a combination of both. Dianabol aromatizes rather heavily, which means in a stack with another aromatizing compound the risk for gyno remains high and water retention is virtually a fact. Post-cycle the use of Clomid or Nolvadex can be employed to boost natural testosterone production. There is quite some circulating estrogen post-cycle that causes prolonged negative feedback, clomid or Nolvadex would solve that problem and help you retain more of your gains.

References

1 Serakovskii S, Mats'koviak I., Effect of methanedienone (methandrostenolone) on energy processes and carbohydrate metabolism in rat liver cells, Farmakol Toksikol 1981 Mar-Apr;44(2):213-7

2 Blasberg ME, Langan CJ, Clark AS., The effects of 17 alpha-methyltestosterone, methandrostenolone, and nandrolone decanoate on the rat estrous cycle, Physiol Behav 1997 Feb;61(2):265-72

3 Harrison LM, Fennessey PV., Methandrostenolone metabolism in humans: potential problems associated with isolation and identification of metabolites, Steroid Biochem 1990 Aug 14;36(5):407-14

4 Nesterin MF, Budik VM, Narodetskaia RV, Solov'eva GI, Stoianova VG., Effect of methandrostenolone on liver morphology and enzymatic activity, Farmakol Toksikol 1980 Sep-Oct;43(5):597-601

5 Romics L, Bretan M, Szigeti A, Varsanyi-Nagy M., Effect of methandrostenolone on serum triglyceride and cholesterol levels in diabetic patients, Acta Med Acad Sci Hung 1975, 32(1): 27-34

6 Hervey GR, Hutchinson I, Knibbs AV, Burkinshaw L, Jones PR, Norgan NG, Levell MJ., Anabolic" effects of methandienone in men undergoing athletic training., Lancet 1976 Oct 2;2(7988):699-702
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Cannons

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Re: can someone explain D-bol...?

Post by Cannons on Wed Apr 05, 2017 2:37 pm

Hey pincrusher, do you have anymore info? That was kind of vague. LOL!! :wink: Laughing


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pincrusher

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Re: can someone explain D-bol...?

Post by pincrusher on Wed Apr 05, 2017 3:39 pm


i actually edited that article a little bit or it might have been way to long and nobody would have read the whole thing Laughing
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Cannons

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Re: can someone explain D-bol...?

Post by Cannons on Wed Apr 05, 2017 4:32 pm

I figured that, I was being sarcastic (I know you know that! LOL!) :wink:


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giantkilr

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Re: can someone explain D-bol...?

Post by giantkilr on Wed Apr 05, 2017 5:19 pm

thanks. Laughing


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Cannons

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Re: can someone explain D-bol...?

Post by Cannons on Thu Apr 06, 2017 12:46 am

Hey bigguy, you can put it at the end as well. I haven't done this yet but I'm gonna do it in the cycle I'm on now. Do it for the last 4 weeks or so all the way up to your PCT. I heard it really stimulates some more growth that you may not have gotten bofore. I love dbol!!


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BrotherIron

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Re: can someone explain D-bol...?

Post by BrotherIron on Thu Apr 06, 2017 1:39 am

Big bump to what Cannons just told ya. I would run it in the begining and at the end.


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Re: can someone explain D-bol...?

Post by DoubleWide on Thu Apr 06, 2017 2:36 am

i used the British Dragon 10mgs dbol and it was amazing. id put it right up there with naps. might even be better since its 10mgs tabs. less to take. i loved it.
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pincrusher

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Re: can someone explain D-bol...?

Post by pincrusher on Thu Apr 06, 2017 3:16 am

bump cannons advise.
just make sure you leave at least 4 weeks between the 2 runs of dbol to allow your liver a break from the 17aa. if a 10 week cycle you could run it the 2nd time in weeks 9-12 and start pct week 13.

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